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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
Building Blocks
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
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Services
Custom Synthesis
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Name Index S
SAR-7334 HCl
(Catalog# : 17101610, Cas# :
1333207-63-8
)
SAR7334 is a novel, highly potent and bioavailable inhibitor of TRPC6 channels that o
SEN-826
(Catalog# : 1710168, Cas# :
1160833-51-1
)
SEN-826 is a potential anticancer agent.
SRT3025 HCl
(Catalog# : 17101310, Cas# :
2070015-26-6
)
SRT3025 is an orally available small molecule activator of the SIRT1 enzyme.
Senexin A
(Catalog# : 1710136, Cas# :
1366002-50-7
)
Senexin A is a potent and selective CDK8 inhibitor (IC50 = 280 nM). Senexin A binds t
S63845
(Catalog# : 171071, Cas# :
1799633-27-4
)
S63845 is a small molecule that specifically binds with high affinity to the BH3-bind
Salermide
(Catalog# : 1791511, Cas# :
1105698-15-4
)
Salermide is a Sirtuin inhibitor with a strong cancer-specific proapoptotic effect. S
SD-06
(Catalog# : 1791320, Cas# :
271576-80-8
)
SD-06 is a MAPK p38 alpha inhibitor for the treatment of arthritis.
Sulfatinib
(Catalog# : 179135, Cas# :
1308672-74-3
)
Sulfatinib is an orally bioavailable, small molecule inhibitor of vascular endothelia
S107 HCl
(Catalog# : 1791111, Cas# :
927871-76-9
)
S107 is a Type 1 ryanodine receptor (RyR1) stabilizer; binds RyR1 and enhances the bi
Sematilide hydrochloride
(Catalog# : 179830, Cas# :
101526-62-9
)
Sematilide, also known as CK-1752, is a class III antiarrhythmic. It is a selective d
SNX-2112
(Catalog# : 179815, Cas# :
908112-43-6
)
SNX-2112, also known as PF 04928473, is an Hsp90 inhibitor which is currently undergo
SU-1498
(Catalog# : 17984, Cas# :
168835-82-3
)
SU 1498 is a selective inhibitor of the receptor tyrosine kinase VEGF receptor 2 (VEG
SF2523
(Catalog# : 17918, Cas# :
1174428-47-7
)
SF2523 is a highly selective and potent dual pan-PI3K/BRD4 inhibitor. SF2523 exhibits
SAR-20347
(Catalog# : 1781101, Cas# :
1450881-55-6
)
SAR-20347 is a potent dual inhibitor of JAK1 and tyrosine kinase 2 (TYK2).
SB756050
(Catalog# : 20178811, Cas# :
447410-57-3
)
SB-756050 is a G protein-coupled bile acid receptor 1 (GPBAR1) agonist potentially fo
SAR-405
(Catalog# : 2017882, Cas# :
1523406-39-4
)
<span style="color:#34495E;font-family:" font-size:14px;background-color
Seco Rapamycin (sodium salt)
(Catalog# : 20177313, Cas# :
148554-65-8
)
Seco-rapamycin is the first in vivo open-ring metabolite of rapamycin that does not a
SU5402
(Catalog# : 174191, Cas# :
215543-92-3
)
SU5402 is a fibroblast growth factor receptor (FGFR)-specific tyrosine kinase inhibit
SAR-020106
(Catalog# : 17031004, Cas# :
1184843-57-9
)
SAR-020106 is an ATP-competitive, potent, and selective CHK1 inhibitor with an IC50
SH5-07
(Catalog# : 17031002, Cas# :
1456632-41-9
)
SH5-07 is a robust hydroxamic acid-based STAT3 inhibitor, which induce antitumor ce
SUN11602
(Catalog# : 17030603, Cas# :
704869-38-5
)
SUN11602 is a novel aniline compound, which mimics the neuroprotective mechanisms of
Sardomozide HCl
(Catalog# : 17030306, Cas# :
138794-73-7
)
Sardomozide , also known as SAM486A or CGP48664, is a second-generation polyamine syn
Sacubitril sodium
(Catalog# : 17030108, Cas# :
149690-05-1
)
Sacubitril, also known as AHU377, is angiotensin receptor neprilysin inhibitor being
SHP099 free base
(Catalog# : 17030107, Cas# :
1801747-42-1
)
SHP099 is a potent, selective, orally bioavailable, and efficacious SHP2 inhibitor wi
Semagacestat
(Catalog# : 17022802, Cas# :
425386-60-3
)
Semagacestat (LY450139) is a -secretase blocker for A42, A40 and A38 with IC50 of 10.
(S)-Tedizolid
(Catalog# : 17021402, Cas# :
1431699-67-0
)
Tedizolid is the active moiety of the prodrug tedizolid phosphate, with high potency
STO-609
(Catalog# : 17021319, Cas# :
52029-86-4
)
STO-609 is a specific inhibitor of the Ca2+/Calmodulin-dependent protein kinase kina
S49076
(Catalog# : 17021309, Cas# :
1265965-22-7
)
S49076 is a novel, potent inhibitor of MET, AXL/MER, and FGFR1/2/3 with IC50 valu
SRT2183
(Catalog# : 17021306, Cas# :
1001908-89-9
)
SRT2183 is a small-molecule activator of the sirtuin subtype SIRT1, currently being
SW044248
(Catalog# : 17011714, Cas# :
522650-83-5
)
SW044248 is a potent and selective Topoisomerase I inhibitor. SW044248 killed approxi
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
Zelasudil
(Catalog# : 24014, Cas# :
2365193-22-0
)
Zelasudil is a potent, highly selective and orally-active inhibitor that targets Rho-
Ziftomenib ( KO-539 )
(Catalog# : 24013, Cas# :
2134675-36-6
)
Ziftomenib is an oral, potent, and selective small molecule inhibitor that targets th
Zunsemetinib
(Catalog# : 24012, Cas# :
1640282-42-3
)
Zunsemetinib is an investigational oral mitogen-activated protein kinase-activated pr
Zongertinib
(Catalog# : 24011, Cas# :
2728667-27-2
)
Zongertinib [BI 1810631] is a human epidermal growth factor receptor 2 (HER2) inhibit
Zasocitinib
(Catalog# : 24010, Cas# :
2272904-53-5
)
Zasocitinib is under development for the treatment of moderate to severe plaque psori
RNK-05047
(Catalog# : 24008, Cas# :
2503036-46-0
)
RNK-05047 is a PROTAC degrader of BRD4 which displays significant tumor growth inhibi
Asengeprast (FT011)
(Catalog# : 24009, Cas# :
1001288-58-9
)
Asengeprast (FT011) is an anti-fibrotic agent thatreduces mRNA expression of collagen
ERAS-801 ( JGK-068S )
(Catalog# : 20635, Cas# :
2490431-16-6
)
ERAS-801 ( JGK-068S ) is a potent EGFR inhibitor.
T-1095
(Catalog# : 24004, Cas# :
209746-59-8
)
T-1095 is a potent and selective inhibitor of Na+-glucose cotransporters (SGLTs).
NVL-655 ( ALK-IN-27 )
(Catalog# : 24003, Cas# :
2739866-40-9
)
NVL-655 is a novel, brain-penetrant, ALK-selective inhibitor that was designed to add