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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
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TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
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Metabolism
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
Building Blocks
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
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Indoles and Oxindoles
Iodos
Nitro Compounds
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Phenols
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Pyridines
Pyrimidines
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Name Index T
TP0463518
(Catalog# : 1812282, Cas# :
1558021-37-0
)
TP0463518 is a novel, highly potent HIF prolyl hydroxylase (PHD) inhibitor. TP0463518
Thiamet G
(Catalog# : 1812133, Cas# :
1009816-48-1
)
Thiamet G is a potent and selective inhibitor of O-GlcNAcase.
Talmapimod HCl
(Catalog# : 181252, Cas# :
309915-12-6
)
Talmapimod, also known as SCIO-469, is an orally bioavailable, small-molecule, p38 mi
TG4-155
(Catalog# : 181232, Cas# :
1164462-05-8
)
TG4-155 is a brain penetrant EP2 antagonist (KB = 2.4 nM) that is over 1000-fold less
Tebanicline HCl
(Catalog# : 181231, Cas# :
203564-54-9
)
Tebanicline, also known as ABT-594 and Ebanicline, a potent synthetic nicotinic (non-
Topotecan
(Catalog# : 1811212, Cas# :
123948-87-8
)
Topocecan is a semisynthetic derivative of camptothecin with antineoplastic activity.
TAS-120
(Catalog# : 1811191, Cas# :
1448169-71-8
)
TAS-120 is an orally bioavailable inhibitor of the fibroblast growth factor receptor
Tulrampator ( CX-1632 )
(Catalog# : 1811161, Cas# :
1038984-31-4
)
Tulrampator, also known as S-47445 and CX-1632, is a positive allosteric modulator (P
Thiazovivin
(Catalog# : 1811122, Cas# :
1226056-71-8
)
Thiazovivin is a selective, cell-permeable small molecule that inhibits ROCK activity
TH 1217
(Catalog# : 1811021, Cas# :
1862212-48-3
)
TH 1217 is a potent dCTP pyrophosphatase 1 inhibitor.
TW-37
(Catalog# : 18831, Cas# :
877877-35-5
)
TW-37 is a small-molecule inhibitor of Bcl-2 family proteins, inhibited cell growth a
TAK-715
(Catalog# : 187202, Cas# :
303162-79-0
)
TAK-715 is a potent p38 MAPK inhibitor. which displays potent inhibitory activity and
TAK-960
(Catalog# : 18762, Cas# :
1137868-52-0
)
TAK-960 is an orally available PLK1 inhibitor with potential antineoplastic activity.
Theliatinib
(Catalog# : 186235, Cas# :
1353644-70-8
)
Theliatinib, also known as HMPL-309, is a novel small molecule, epidermal growth fact
Tucidinostat
(Catalog# : 186233, Cas# :
1616493-44-7
)
Tucidinostat is a benzamide type inhibitor of histone deacetylase (HDAC) isoenzymes 1
Takinib
(Catalog# : 18672, Cas# :
1111556-37-6
)
Takinib is a selective TAK1 inhibitor that induces apoptosis following TNF-α stimula
TMP269
(Catalog# : 185254, Cas# :
1314890-29-3
)
TMP269 is a highly potent, selective and cell-permeable class IIa HDAC inhibitor with
Trilaciclib (G1T28)
(Catalog# : 185235, Cas# :
1374743-00-6
)
TRILACICLIB (G1T28), A HIGHLY POTENT, TRANSIENT CDK 4/6 INHIBITOR WITHIC50s OF 1 nM A
TAPI-1
(Catalog# : 185181, Cas# :
171235-71-5
)
TAPI-1 is and inhibitor of TACE. It inhibits the cleavage of TNF-a, TNFRI (p60), and
TG100572 HCl
(Catalog# : 185175, Cas# :
867331-64-4
)
TG-100572 is a potent and selective VEGFR2/Src kinase inhibitor.
TLN-232
(Catalog# : 18594, Cas# :
158899-10-6
)
TLN-232, also known as CAP-232, is a synthetic cyclic heptapeptide with potential ant
TRC051384
(Catalog# : 18593, Cas# :
867164-40-7
)
TRC051384 is a inducer of heat shock protein Hsp70.
Triptorelin Acetate
(Catalog# : 18592, Cas# :
140194-24-7
)
Triptorelin is a gonadotropin-releasing hormone agonist (GnRH agonist) used as the ac
Tropifexor
(Catalog# : 18591, Cas# :
1383816-29-2
)
Tropifexor, also known as LJN452, is a farnesoid X receptor agonist for the Treatment
THZ531
(Catalog# : 184172, Cas# :
1702809-17-3
)
THZ531 is a covalent CDK12 and CDK13 covalent inhibitor. Cyclin-dependent kinases 12
Tofogliflozin
(Catalog# : 184311, Cas# :
903565-83-3
)
Tofogliflozin, also known as CSG 452, is a potent and high selective SGLT2 inhibitor
TPX-0005
(Catalog# : 18423, Cas# :
1802220-02-5
)
TPX-0005 is a Src/FAK/Janus kinase 2 (JAK2) inhibitor. TPX-0005 plus EGFR TKI suppres
tert-butyl ((1H-benzo[d][1,2,3]triazol-1-yl)methyl)carbamate
(Catalog# : 183214, Cas# :
305860-41-7
)
tert-butyl (1H-benzo[d][1,2,3]triazol-1-yl)methylcarbamate是一种药物中间体。
Timapiprant
(Catalog# : 1712152, Cas# :
851723-84-7
)
Timapiprant,又名OC000459,是一种强效、选择性和口服的CRTH2拮抗剂。
TUG-770
(Catalog# : 1791519, Cas# :
1402601-82-4
)
TUG-770 is a Highly Potent Free Fatty Acid Receptor 1 (FFA1/GPR40) Agonist for Treatm
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
Zelasudil
(Catalog# : 24014, Cas# :
2365193-22-0
)
Zelasudil is a potent, highly selective and orally-active inhibitor that targets Rho-
Ziftomenib ( KO-539 )
(Catalog# : 24013, Cas# :
2134675-36-6
)
Ziftomenib is an oral, potent, and selective small molecule inhibitor that targets th
Zunsemetinib
(Catalog# : 24012, Cas# :
1640282-42-3
)
Zunsemetinib is an investigational oral mitogen-activated protein kinase-activated pr
Zongertinib
(Catalog# : 24011, Cas# :
2728667-27-2
)
Zongertinib [BI 1810631] is a human epidermal growth factor receptor 2 (HER2) inhibit
Zasocitinib
(Catalog# : 24010, Cas# :
2272904-53-5
)
Zasocitinib is under development for the treatment of moderate to severe plaque psori
RNK-05047
(Catalog# : 24008, Cas# :
2503036-46-0
)
RNK-05047 is a PROTAC degrader of BRD4 which displays significant tumor growth inhibi
Asengeprast (FT011)
(Catalog# : 24009, Cas# :
1001288-58-9
)
Asengeprast (FT011) is an anti-fibrotic agent thatreduces mRNA expression of collagen
ERAS-801 ( JGK-068S )
(Catalog# : 20635, Cas# :
2490431-16-6
)
ERAS-801 ( JGK-068S ) is a potent EGFR inhibitor.
T-1095
(Catalog# : 24004, Cas# :
209746-59-8
)
T-1095 is a potent and selective inhibitor of Na+-glucose cotransporters (SGLTs).
NVL-655 ( ALK-IN-27 )
(Catalog# : 24003, Cas# :
2739866-40-9
)
NVL-655 is a novel, brain-penetrant, ALK-selective inhibitor that was designed to add