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(+)-MK801(maleate)

Catalog No: 71903
CAS Number: 77086-22-7
Purity: 98% by HPLC 

(+)-MK-801 is an uncompetitive antagonist of the N-Methyl-D-aspartate (NMDA) receptor, a glutamate receptor discovered by a team at Merck in 1982.  (+)-MK-801 has been shown to bind to and inhibit the serotonin and dopamine transporters as well.

 

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Chemical Information

Name(+)-MK801(maleate)
Iupac Chemical Name(5S,10R)-(+)-5-Methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine maleate 
SynonymsDizocilpine maleate, Dizocilpine 
Molecular FormulaC16H15N.C4H4O4 
Molecular Weight337.37 
SmileC[C@]12c3ccccc3C[C@H](N1)c4c2cccc4.C(=C\C(=O)O)\C(=O)O
InChiKeyQLTXKCWMEZIHBJ-FWHYOZOBSA-N
InChiInChI=1S/C16H15N.C4H4O4/c1-16-13-8-4-2-6-11(13)10-15(17-16)12-7-3-5-9-14(12)16;5-3(6)1-2-4(7)8/h2-9,15,17H,10H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1-/t15-,16+;/m0./s1
CAS Number77086-22-7
MDLMFCD00082466
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Ordering Information

PackagingPriceAvailabilityPurityShipping Time
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Formulationcrystalline solid 
Purity98% by HPLC 
Storage3 years -20ºCpowder 6 months-80ºCin solvent 
SolubilitySoluble in DMSO 
Handling
Shipping ConditionShipped under ambient temperature 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

71903 - (+)-MK801(maleate) | CAS 77086-22-7

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