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A-119637

Catalog No: 204603
CAS Number: 255713-47-4
Purity: 98% Min.

 A-119637 is a novel, selective and potent alpha1D antagonist.

For research use only. We do not sell to patients.

Chemical Information

NameA-119637
Iupac Chemical Name3-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]-5-phenyl-1H-thieno[3,2-e]pyrimidine-2,4-dione
SynonymsA-119637
Molecular FormulaC25H26N4O3S
Molecular Weight462.568
SmileO=C1N(CCN2CCN(C3=CC=CC=C3OC)CC2)C(C(C(C4=CC=CC=C4)=CS5)=C5N1)=O
InChiKey HLVQBOYEHQRWHG-UHFFFAOYSA-N
InChiInChI=1S/C25H26N4O3S/c1-32-21-10-6-5-9-20(21)28-14-11-27(12-15-28)13-16-29-24(30)22-19(18-7-3-2-4-8-18)17-33-23(22)26-25(29)31/h2-10,17H,11-16H2,1H3,(H,26,31)
CAS Number255713-47-4
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Ordering Information

PackagingPriceAvailabilityPurityShipping Time
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FormulationSolid powder
Purity98% Min.
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
SolubilitySoluble in DMSO
Handling
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study

1: Mizusawa H, Hedlund P, Sjunnesson J, Brioni JD, Sullivan JP, Andersson KE. Enhancement of apomorphine-induced penile erection in the rat by a selective alpha(1D)-adrenoceptor antagonist. Br J Pharmacol. 2002 Jul;136(5):701-8. PubMed PMID: 12086979; PubMed Central PMCID: PMC1573401.

2: Carroll WA, Sippy KB, Esbenshade TA, Buckner SA, Hancock AA, Meyer MD. Two novel and potent 3-[(o-methoxyphenyl)piperazinylethyl]-5-phenylthien. Bioorg Med Chem Lett. 2001 May 7;11(9):1119-21. PubMed PMID: 11354357.


Chemical Structure

204603 - A-119637 | CAS 255713-47-4

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