A-1293201
Catalog No: 204604
CAS Number: 1375557-33-7
Purity: 98% Min.
A-1293201 is a potent and selective NAMPT inhibitor.
For research use only. We do not sell to patients.
Chemical Information
| Name | A-1293201 |
|---|---|
| Iupac Chemical Name | (S)-N-(4-(((tetrahydrofuran-3-yl)methyl)carbamoyl)phenyl)isoindoline-2-carboxamide |
| Synonyms | A-1293201; A 1293201; A1293201; |
| Molecular Formula | C21H23N3O3 |
| Molecular Weight | 365.433 |
| Smile | O=C(N1CC2=C(C=CC=C2)C1)NC3=CC=C(C(NC[C@H]4COCC4)=O)C=C3 |
| InChiKey | BLZJCPAXCWJANZ-HNNXBMFYSA-N |
| InChi | InChI=1S/C21H23N3O3/c25-20(22-11-15-9-10-27-14-15)16-5-7-19(8-6-16)23-21(26)24-12-17-3-1-2-4-18(17)13-24/h1-8,15H,9-14H2,(H,22,25)(H,23,26)/t15-/m0/s1 |
| CAS Number | 1375557-33-7 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | 98% Min. |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
1: Guo J, Lam LT, Longenecker KL, Bui MH, Idler KB, Glaser KB, Wilsbacher JL, Tse
C, Pappano WN, Huang TH. Identification of novel resistance mechanisms to NAMPT
inhibition via the de novo NAD(+) biosynthesis pathway and NAMPT mutation.
Biochem Biophys Res Commun. 2017 Sep 23;491(3):681-686. doi:
10.1016/j.bbrc.2017.07.143. Epub 2017 Jul 26. PubMed PMID: 28756225.
Chemical Structure
