A66 is a potent and specific p110 inhibitor with IC50 of 32 nM, >100 fold selectivity for p110 over other class-I PI3K isoforms.
For research use only. We do not sell to patients.
Name | A66 |
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Iupac Chemical Name | (2S)-1-N-[5-(2-tert-butyl-1,3-thiazol-4-yl)-4-methyl-1,3-thiazol-2-yl]pyrrolidine-1,2-dicarboxamide |
Synonyms | A-66; A 66 |
Molecular Formula | C17H23N5O2S2 |
Molecular Weight | 393.52 |
Smile | CC1=C(SC(=N1)NC(=O)N2CCCC2C(=O)N)C3=CSC(=N3)C(C)(C)C |
InChiKey | HBPXWEPKNBHKAX-UHFFFAOYSA-N |
InChi | InChI=1S/C17H23N5O2S2/c1-9-12(10-8-25-14(20-10)17(2,3)4)26-15(19-9)21-16(24)22-7-5-6-11(22)13(18)23/h8,11H,5-7H2,1-4H3,(H2,18,23)(H,19,21,24) |
CAS Number | 1166227-08-2 |
Related CAS |
Packaging | Price | Availability | Purity | Shipping Time |
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Bulk | Enquiry | Enquiry | Enquiry |
Formulation | Solid powder |
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Purity | 98% |
Storage | -20 ºC for 3 years |
Solubility | Soluble in DMSO |
Handling | |
Shipping Condition | Shipped under ambient temperature |
HS Code |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study |