AEE788
Catalog No: 52750
CAS Number: 497839-62-0
Purity: 98%
AEE788(NVP-AEE 788) is a potent inhibitor of EGFR and HER2/ErbB2 with IC50 of 2 nM and 6 nM, less potent to VEGFR2/KDR, c-Abl, c-Src, and Flt-1, does not inhibit Ins-R, IGF-1R, PKC and CDK1.
For research use only. We do not sell to patients.
Chemical Information
| Name | AEE788 |
|---|---|
| Molecular Formula | C27H32N6 |
| Molecular Weight | 440.58 |
| Smile | CCN1CCN(CC1)Cc2ccc(cc2)c3cc-4c(nc[nH]c4n3)N[C@H](C)c5ccccc5 |
| InChiKey | FZKTWZZPPTUYSG-GQJKKZBQSA-N |
| InChi | InChI=1S/C27H40N6/c1-3-32-13-15-33(16-14-32)18-21-9-11-23(12-10-21)25-17-24-26(28-19-29-27(24)31-25)30-20(2)22-7-5-4-6-8-22/h4-12,20,24-31H,3,13-19H2,1-2H3/t20-,24?,25?,26?,27?/m1/s1 |
| CAS Number | 497839-62-0 |
| MDL | MFCD11100351 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Purity | 98% |
|---|---|
| Solubility | DMSO 88 mg/mL; Water <1 mg/mL; Ethanol <1 mg/mL |
| Handling | |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
