AG-494, also known as Tyrphostin AG-494, is an inhibitor of epidermal growth factor receptor kinase with an IC50 value of 1 µM in HT-22 cells.
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Chemical Information
Name | AG-494 |
Iupac Chemical Name | 2E-cyano-3-(3,4-dihydroxyphenyl)-N-phenyl-2-propenamide |
Synonyms | AG-494; AG 494; AG494; |
Molecular Formula | C16H12N2O3 |
Molecular Weight | 280.283 |
Smile | O=C(NC1=CC=CC=C1)/C(C#N)=C/C2=CC=C(O)C(O)=C2 |
InChiKey | HKHOVJYOELRGMV-XYOKQWHBSA-N |
InChi | InChI=1S/C16H12N2O3/c17-10-12(8-11-6-7-14(19)15(20)9-11)16(21)18-13-4-2-1-3-5-13/h1-9,19-20H,(H,18,21)/b12-8+ |
CAS Number | 133550-35-3 |
Related CAS | |
Ordering Information
Packaging | Price | Availability | Purity | Shipping Time |
Bulk | | Enquiry | Enquiry | Enquiry |
Formulation | Off-white solid to white solid |
Purity | >98% |
Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
Solubility | Soluble in DMSO |
Handling | |
Shipping Condition | Shipped under ambient temperature |
HS Code | |
Targets | |
Mechanism | |
Cell study | |
Animal study | |
Clinical study | |