AGI-5198 is a novel R132H-IDH1 inhibitor, identified through a high-throughput screen blocked R132H-IDH1 activity in a dose-dependent manner.
For research use only. We do not sell to patients.
Name | AGI-5198 |
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Iupac Chemical Name | N-cyclohexyl-2-(3-fluoro-N-[2-(2-methylimidazol-1-yl)acetyl]anilino)-2-(2-methylphenyl)acetamide |
Synonyms | AGI5198; AGI 5198 ; IDHC35 |
Molecular Formula | C27H31FN4O2 |
Molecular Weight | 462.56 |
Smile | O=C(NC1CCCCC1)C(N(C2=CC=CC(F)=C2)C(CN3C=CN=C3C)=O)C4=CC=CC=C4C |
InChiKey | FNYGWXSATBUBER-UHFFFAOYSA-N |
InChi | InChI=1S/C27H31FN4O2/c1-19-9-6-7-14-24(19)26(27(34)30-22-11-4-3-5-12-22)32(23-13-8-10-21(28)17-23)25(33)18-31-16-15-29-20(31)2/h6-10,13-17,22,26H,3-5,11-12,18H2,1-2H3,(H,30,34) |
CAS Number | 1355326-35-0 |
Related CAS |
Packaging | Price | Availability | Purity | Shipping Time |
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Formulation | white solid solid |
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Purity | 98% |
Storage | -20 ºC for 3 years |
Solubility | Soluble in DMSO |
Handling | |
Shipping Condition | Shipped under ambient temperature |
HS Code |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study |