AG 490
Catalog No: 122210
CAS Number: 134036-52-5
Purity: 98%
AG-490 is a tyrosine kinase inhibitor of JAK2, EGFR, and Neu that belongs to the family of tyrphostins. In acute lymphoblastic leukemia studies the compound has been reported to inhibit JAK2 from B cell precursors.
For research use only. We do not sell to patients.
Chemical Information
| Name | AG 490 |
|---|---|
| Iupac Chemical Name | N-benzyl-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamide |
| Synonyms | Tyrphostin B42 |
| Molecular Formula | C17H14N2O3 |
| Molecular Weight | 294.305 |
| Smile | C1=CC=C(C=C1)CNC(=O)/C(=C/C2=CC(=C(C=C2)O)O)/C#N |
| InChiKey | TUCIOBMMDDOEMM-RIYZIHGNSA-N |
| InChi | InChI=1S/C17H14N2O3/c18-10-14(8-13-6-7-15(20)16(21)9-13)17(22)19-11-12-4-2-1-3-5-12/h1-9,20-21H,11H2,(H,19,22)/b14-8+ |
| CAS Number | 134036-52-5 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | 98% |
| Storage | -20 ºC for 3 years |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
