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AKT inhibitor

Catalog No: 611803
CAS Number: 1004990-28-6
Purity: 98% 

AKT inhibitor is a broadly selective, potent, ATP-competitive Akt inhibitor, displays 900-fold greater selectivity for PKB (IC50 = 0.5 nM) than PKA (IC50=450 nM).

 

For research use only. We do not sell to patients.

Chemical Information

NameAKT inhibitor
Iupac Chemical NameN-[[(3S)-3-AMINO-1-(5-ETHYL-7H-PYRROLO[2,3-D]PYRIMIDIN-4-YL)-3-PYRROLIDINYL]METHYL]-2,4-DIFLUORO-BENZAMIDE 
SynonymsAKT inhibitor;AKT protein kinase inhibitor 
Molecular FormulaC20H22F2N6O 
Molecular Weight400.43 
SmileN[C@]1(CN(CC1)C=1C2=C(N=CN1)NC=C2CC)CNC(C2=C(C=C(C=C2)F)F)=O
InChiKeyMOZRQQTUYAYCQT-FQEVSTJZSA-N
InChiInChI=1S/C20H22F2N6O/c1-2-12-8-24-17-16(12)18(27-11-26-17)28-6-5-20(23,10-28)9-25-19(29)14-4-3-13(21)7-15(14)22/h3-4,7-8,11H,2,5-6,9-10,23H2,1H3,(H,25,29)(H,24,26,27)/t20-/m0/s1
CAS Number1004990-28-6
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Ordering Information

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Formulationcrystalline solid 
Purity98% 
Storage3 years -20ºCpowder 
SolubilitySoluble in DMSO 
Handling
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

611803 - AKT inhibitor | CAS 1004990-28-6

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