AM-9747
Catalog No: 24018
CAS Number: 2691869-82-4
Purity: ≧98.0%
AM-9747 is an MTA cooperative PRMT5 inhibitor. AM-9747 selectively inhibited the proliferation of HCT116 MTAP-deleted cells (IC50 = 0.027 μM).
For research use only. We do not sell to patients.
Chemical Information
| Name | AM-9747 |
|---|---|
| Iupac Chemical Name | 2-Amino-3-methyl-N-[(1R)-1-(pyrimidin-2-yl)ethyl]-N-[[5-(trifluoromethyl)pyridin-2-yl]methyl]quinoline-6-carboxamide |
| Synonyms | AM-9747 ; AM 9747 ; AM9747 |
| Molecular Formula | C24H21F3N6O |
| Molecular Weight | 466.47 |
| Smile | O=C(C1=CC=C2N=C(N)C(C)=CC2=C1)N([C@@H](C3=NC=CC=N3)C)CC4=NC=C(C(F)(F)F)C=C4 |
| InChiKey | QRZCNKOBDDQUAP-OAHLLOKOSA-N |
| InChi | InChI=1S/C24H21F3N6O/c1-14-10-17-11-16(4-7-20(17)32-21(14)28)23(34)33(15(2)22-29-8-3-9-30-22)13-19-6-5-18(12-31-19)24(25,26)27/h3-12,15H,13H2,1-2H3,(H2,28,32)/t15-/m1/s1 |
| CAS Number | 2691869-82-4 |
| Related CAS | 2691869-82-4 |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | ≧98.0% |
| Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
| Solubility | Soluble in DMSO (DMSO : ≥ 100 mg/mL) |
| Handling | Refer to MSDS |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code | 2934200090 |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
