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AMG-319

Catalog No: 52026
CAS Number: 1608125-21-8
Purity: 98% 

AMG 319 is an investigational, highly selective, small molecule inhibitor of PI3K that blocks B cell proliferation following BCR stimulation both in vitro and in vivo, inhibits basal AKT phosphorylation, and inhibits proliferation in lymphoid tumor cells.

 

For research use only. We do not sell to patients.

Chemical Information

NameAMG-319
Iupac Chemical Name(S)-N-(1-(7-fluoro-2-(pyridin-2-yl)quinolin-3-yl)ethyl)-9H-purin-6-amine 
SynonymsAMG-319; AMG319; AMG 319. 
Molecular FormulaC21H16FN7 
Molecular Weight385.40 
SmileC[C@H](NC1=C2N=CNC2=NC=N1)C3=CC4=CC=C(F)C=C4N=C3C5=NC=CC=C5
InChiKeyKWRYMZHCQIOOEB-LBPRGKRZSA-N
InChiInChI=1S/C21H16FN7/c1-12(28-21-19-20(25-10-24-19)26-11-27-21)15-8-13-5-6-14(22)9-17(13)29-18(15)16-4-2-3-7-23-16/h2-12H,1H3,(H2,24,25,26,27,28)/t12-/m0/s1
CAS Number1608125-21-8
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Ordering Information

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Formulationcrystalline solid 
Purity98% 
Storage3 years -20ºCpowder 
SolubilitySoluble in DMSO 
Handling
Shipping ConditionShipped under ambient temperature 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

52026 - AMG-319 | CAS 1608125-21-8

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