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AMG 487

Catalog No: 122942
CAS Number: 473719-41-4
Purity: 98% 

AMG 487 is a small molecule antagonist of the chemokine receptor CXCR3. 

For research use only. We do not sell to patients.

Chemical Information

NameAMG 487
Iupac Chemical NameN-[(1R)-1-[3-(4-ethoxyphenyl)-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-N-(pyridin-3-ylmethyl)-2-[4-(trifluoromethoxy)phenyl]acetamide 
SynonymsAMG487; AMG-487 
Molecular FormulaC32H28F3N5O4 
Molecular Weight603.591 
SmileCCOC1=CC=C(C=C1)N2C(=O)C3=C(N=CC=C3)N=C2C(C)N(CC4=CN=CC=C4)C(=O)CC5=CC=C(C=C5)OC(F)(F)F
InChiKeyWQTKNBPCJKRYPA-UHFFFAOYSA-N
InChiInChI=1S/C32H28F3N5O4/c1-3-43-25-14-10-24(11-15-25)40-30(38-29-27(31(40)42)7-5-17-37-29)21(2)39(20-23-6-4-16-36-19-23)28(41)18-22-8-12-26(13-9-22)44-32(33,34)35/h4-17,19,21H,3,18,20H2,1-2H3
CAS Number473719-41-4
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Ordering Information

PackagingPriceAvailabilityPurityShipping Time
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FormulationSolid powder 
Purity98% 
Storage-20 ºC for 3 years 
SolubilitySoluble in DMSO 
Handling
Shipping ConditionShipped under ambient temperature 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

122942 - AMG 487 | CAS 473719-41-4

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