ARS-1620 is an atropisomeric selective KRAS-G12C inhibitor with desirable pharmacokinetics.
For research use only. We do not sell to patients.
Name | ARS-1620 |
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Iupac Chemical Name | (S)-1-(4-(6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)quinazolin-4-yl)piperazin-1-yl)prop-2-en-1-one |
Synonyms | ARS-1620; ARS 1620; ARS1620; |
Molecular Formula | C21H17ClF2N4O2 |
Molecular Weight | 430.8398 |
Smile | C=CC(N1CCN(C2=C3C=C(Cl)[C@@]([C@@]4=C(O)C=CC=C4F)=C(F)C3=NC=N2)CC1)=O |
InChiKey | ZRPZPNYZFSJUPA-UHFFFAOYSA-N |
InChi | InChI=1S/C21H17ClF2N4O2/c1-2-16(30)27-6-8-28(9-7-27)21-12-10-13(22)17(19(24)20(12)25-11-26-21)18-14(23)4-3-5-15(18)29/h2-5,10-11,29H,1,6-9H2 |
CAS Number | 1698055-85-4 |
Related CAS |
Packaging | Price | Availability | Purity | Shipping Time |
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Bulk | Enquiry | Enquiry | Enquiry |
Formulation | Off-white solid to white solid |
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Purity | >98% |
Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
Solubility | Soluble in DMSO |
Handling | |
Shipping Condition | Shipped under ambient temperature |
HS Code |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study |