AS-252424 is a potent and selective small-molecule PI3Kgamma inhibitor. Oral administration of AS-252424 in a mouse model of acute peritonitis led to a significant reduction of leukocyte recruitment.
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Name | AS-252424 |
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Iupac Chemical Name | (Z)-5-((5-(4-fluoro-2-hydroxyphenyl)furan-2-yl)methylene)thiazolidine-2,4-dione |
Synonyms | AS252424; AS 252424; AS-252424. |
Molecular Formula | C14H8FNO4S |
Molecular Weight | 305.28 |
Smile | FC1=CC(=C(C=C1)C1=CC=C(O1)\C=C/1\C(NC(S1)=O)=O)O |
InChiKey | OYYVWNDMOQPMGE-SDQBBNPISA-N |
InChi | InChI=1S/C14H8FNO4S/c15-7-1-3-9(10(17)5-7)11-4-2-8(20-11)6-12-13(18)16-14(19)21-12/h1-6,17H,(H,16,18,19)/b12-6- |
CAS Number | 900515-16-4 |
Related CAS |
Packaging | Price | Availability | Purity | Shipping Time |
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Bulk | Enquiry | Enquiry | Enquiry |
Formulation | Solid powder |
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Purity | 98% by HPLC |
Storage | -20 ºC for 3 years |
Solubility | Soluble in DMSO |
Handling | |
Shipping Condition | Shipped under ambient temperature |
HS Code |
Targets | |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study |