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ASLAN003

Catalog No: 20507
CAS Number: 1035688-66-4
Purity: 98% Min.

ASLAN003 is an orally active and potent inhibitor of DHODH (Human Dihydroorotate Dehydrogenase).


For research use only. We do not sell to patients.

Chemical Information

NameASLAN003
Iupac Chemical Name2-((3,5-difluoro-3'-methoxy-[1,1'-biphenyl]-4-yl)amino)nicotinic acid
SynonymsASLAN003; ASLAN 003; ASLAN-003; Aslan-003; Farudodstat
Molecular FormulaC19H14F2N2O3
Molecular Weight356.32
SmileO=C(C1=CC=CN=C1NC2=C(F)C=C(C3=CC=CC(OC)=C3)C=C2F)O
InChiKeyOMPATGZMNFWVOH-UHFFFAOYSA-N
InChiInChI=1S/C19H14F2N2O3/c1-26-13-5-2-4-11(8-13)12-9-15(20)17(16(21)10-12)23-18-14(19(24)25)6-3-7-22-18/h2-10H,1H3,(H,22,23)(H,24,25)
CAS Number1035688-66-4
Related CAS

Ordering Information

PackagingPriceAvailabilityPurityShipping Time
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FormulationSolid powder
Purity98% Min.
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
SolubilitySoluble in DMSO
Handling
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study

1: Marco L. Lolli, et al. Human Dihydroorotate Dehydrogenase (hDHODH) as a new target on Acute Myelogenous Leukemia (AML): Targeting Myeloid Differentiation using Potent and Innovative hDHODH Inhibitors. 23rd Swedish Conference on Macromolecular Structure and Function Tällberg, 14-17 June 2019

Chemical Structure

20507 - ASLAN003 | CAS 1035688-66-4

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