ASN-90 (ASN-120290, FNP-223) is an oral, brain-penetrant, small-molecule inhibitor of the O-GlcNAcase enzyme that shows ability to promote the O-GlcNAcylation of tau and alpha-synuclein in the brain.
For research use only. We do not sell to patients.
Name | ASN-90 ( ASN-120290, FNP-223 ) |
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Iupac Chemical Name | (-)-N-(5-[4-[(1S)-1-(2H-1,3-Benzodioxol-5-yl)ethyl]piperazin-1-yl]-1,3,4-thiadiazol-2-yl)acetamide--hydrogen chloride (1/1) |
Synonyms | ASN-90 ; ASN 90 ; ASN90 ; ASN-120290 ; FNP-223 ; ASN120290 ; FNP223 ; ASN 120290, FNP 223 |
Molecular Formula | C17H22ClN5O3S |
Molecular Weight | 411.91 |
Smile | [H]Cl.CC(NC1=NN=C(N2CCN([C@H](C3=CC=C(OCO4)C4=C3)C)CC2)S1)=O |
InChiKey | BPMOHMBJNBAUBC-MERQFXBCSA-N |
InChi | InChI=1S/C17H21N5O3S.ClH/c1-11(13-3-4-14-15(9-13)25-10-24-14)21-5-7-22(8-6-21)17-20-19-16(26-17)18-12(2)23;/h3-4,9,11H,5-8,10H2,1-2H3,(H,18,19,23);1H/t11-;/m0./s1 |
CAS Number | 2129093-74-7 |
Related CAS | 1884154-02-2 ( Free base ) |
Packaging | Price | Availability | Purity | Shipping Time |
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Bulk | Enquiry | Enquiry | Enquiry |
Formulation | Solid powder |
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Purity | ≧98.0% |
Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
Solubility | Soluble in DMSO (DMSO : ≥ 100 mg/mL) |
Handling | Refer to MSDS |
Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
HS Code | 2934200090 |
Targets | |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study |