AT7519 hydrochloride is a multi-CDK inhibitor for CDK1, 2, 4, 6 and 9 with IC50 of 10-210 nM,which is less potent to CDK3 and little active to CDK7.
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Chemical Information
Name | AT7519 Hydrochloride |
Iupac Chemical Name | 4-[(2,6-dichlorobenzoyl)amino]-N-piperidin-4-yl-1H-pyrazole-5-carboxamide,hydrochloride |
Synonyms | AT 7519 Hydrochloride; AT-7519 Hydrochloride |
Molecular Formula | C16H18Cl3N5O2 |
Molecular Weight | 418.71 |
Smile | Cl.ClC1=C(C(=O)NC=2C(=NNC2)C(=O)NC2CCNCC2)C(=CC=C1)Cl |
InChiKey | PAOFPNGYBWGKCO-UHFFFAOYSA-N |
InChi | InChI=1S/C16H17Cl2N5O2.ClH/c17-10-2-1-3-11(18)13(10)15(24)22-12-8-20-23-14(12)16(25)21-9-4-6-19-7-5-9;/h1-3,8-9,19H,4-7H2,(H,20,23)(H,21,25)(H,22,24);1H |
CAS Number | 902135-91-5 |
MDL | MFCD13185136 |
Related CAS | |
Ordering Information
Packaging | Price | Availability | Purity | Shipping Time |
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Formulation | Solid powder |
Purity | 98% |
Storage | -20 ºC for 3 years |
Solubility | Soluble in DMSO |
Handling | |
Shipping Condition | Shipped under ambient temperature |
HS Code | |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study | |