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AZD-0284

Catalog No: 19365
CAS Number: 2101291-07-8
Purity: >98%

AZD-0284 is a potent, selective, inverse agonist of the nuclear receptor RORγ for the potential treatment of Plaque psoriasis.

For research use only. We do not sell to patients.

Chemical Information

NameAZD-0284
Iupac Chemical Name(R)-2-acetyl-N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)-5-(methylsulfonyl)isoindoline-1-carboxamide
SynonymsAZD-0284; AZD 0284; AZD0284.
Molecular FormulaC21H18F6N2O5S
Molecular Weight524.4344
SmileO=C([C@@H]1N(C(C)=O)CC2=C1C=CC(S(=O)(C)=O)=C2)NC3=CC=C(C(C(F)(F)F)(O)C(F)(F)F)C=C3
InChiKeyQYYZXEPEVBXNNA-QGZVFWFLSA-N
InChiInChI=1S/C21H18F6N2O5S/c1-11(30)29-10-12-9-15(35(2,33)34)7-8-16(12)17(29)18(31)28-14-5-3-13(4-6-14)19(32,20(22,23)24)21(25,26)27/h3-9,17,32H,10H2,1-2H3,(H,28,31)/t17-/m1/s1
CAS Number2101291-07-8
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Ordering Information

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FormulationOff-white solid to white solid
Purity>98%
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
SolubilitySoluble in DMSO
Handling
Shipping ConditionShipped under ambient temperature
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

19365 - AZD-0284 | CAS 2101291-07-8

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