AZD5904 is a potent orally bioavailable MPO inhibitor. In preclinical studies, AZD5904 inhibited the isolated MPO enzyme with an IC50 of 140 nM and was approximately equipotent in assays of rat and mouse MPO enzyme activity.
AZD5904, Bulk in stock, contact us by email for Bulk quotation.
For research use only. We do not sell to patients.
Name | AZD-5904 |
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Iupac Chemical Name | (R)-3-((tetrahydrofuran-2-yl)methyl)-2-thioxo-1,2,3,7-tetrahydro-6H-purin-6-one |
Synonyms | AZ1, AZ 1 AZ-1; TX4; TX-4; TX 4; AZD-5904; AZD 5904; AZD5904. |
Molecular Formula | C10H12N4O2S |
Molecular Weight | 252.292 |
Smile | O=C1NC(N(C[C@@H]2OCCC2)C3=C1NC=N3)=S |
InChiKey | RSPDBEVKURKEII-ZCFIWIBFSA-N |
InChi | InChI=1S/C10H12N4O2S/c15-9-7-8(12-5-11-7)14(10(17)13-9)4-6-2-1-3-16-6/h5-6H,1-4H2,(H,11,12)(H,13,15,17)/t6-/m1/s1 |
CAS Number | 618913-30-7 |
Related CAS | 618913-30-7 |
Packaging | Price | Availability | Purity | Shipping Time |
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Bulk | Enquiry | Enquiry | Enquiry |
Formulation | Light yellow to yellow (Solid) |
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Purity | ≧98.0% |
Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
Solubility | Soluble in DMSO |
Handling | |
Shipping Condition | Shipped under ambient temperature |
HS Code |
Targets | |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study |