AZD2014(Vistusertib)
Catalog No: 71804
CAS Number: 1009298-59-2
Purity: 98% by HPLC
AZD2014 is a potent (IC50 2.81 nM), selective (inactive against 220 other kinases) inhibitor of mTOR kinase. It Inhibited downstream targets of both mTORC1 (pS6 and p4EBP1) and mTORC2 (pAKT s473) in several in vitro models in a dose- and time-dependent manner.
For research use only. We do not sell to patients.
Chemical Information
| Name | AZD2014(Vistusertib) |
|---|---|
| Iupac Chemical Name | 3-[2,4-Bis((3S)-3-methylmorpholin-4-yl)pyrido[5,6-e]pyrimidin-7-yl]-N-methylbenzamide |
| Synonyms | AZD 2014;AZD-2014;AZD2014;Vistusertib |
| Molecular Formula | C25H30N6O3 |
| Molecular Weight | 462.5 |
| Smile | O=C(NC)C1=CC=CC(C2=CC=C3C(N4[C@@H](C)COCC4)=NC(N5[C@@H](C)COCC5)=NC3=N2)=C1 |
| InChiKey | JUSFANSTBFGBAF-IRXDYDNUSA-N |
| InChi | InChI=1S/C25H30N6O3/c1-16-14-33-11-9-30(16)23-20-7-8-21(18-5-4-6-19(13-18)24(32)26-3)27-22(20)28-25(29-23)31-10-12-34-15-17(31)2/h4-8,13,16-17H,9-12,14-15H2,1-3H3,(H,26,32)/t16-,17-/m0/s1 |
| CAS Number | 1009298-59-2 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | crystalline solid |
|---|---|
| Purity | 98% by HPLC |
| Storage | 3 years -20ºCpowder 6 months-80ºCin solvent |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
