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AZD4547

Catalog No: 010820
CAS Number: 1035270-39-3
Purity: 98% 

AZD4547 is a novel selective FGFR inhibitor targeting FGFR1/2/3 with IC50 of 0.2 nM/2.5 nM/1.8 nM, weaker activity against FGFR4, VEGFR2, and little activity observed against IGFR, CDK2, and p38. 

For research use only. We do not sell to patients.

Chemical Information

NameAZD4547
Iupac Chemical NameN-(5-(3,5-dimethoxyphenethyl)-1H-pyrazol-3-yl)-4-((3S,5R)-3,5-dimethylpiperazin-1-yl)benzamide 
SynonymsAZD 4547; AZD-4547 
Molecular FormulaC26H33N5O3 
Molecular Weight463.572 
SmileO=C(NC1=NNC(CCC2=CC(OC)=CC(OC)=C2)=C1)C3=CC=C(N4C[C@H](C)N[C@H](C)C4)C=C3
InChiKeyVRQMAABPASPXMW-HDICACEKSA-N
InChiInChI=1S/C26H33N5O3/c1-17-15-31(16-18(2)27-17)22-9-6-20(7-10-22)26(32)28-25-13-21(29-30-25)8-5-19-11-23(33-3)14-24(12-19)34-4/h6-7,9-14,17-18,27H,5,8,15-16H2,1-4H3,(H2,28,29,30,32)/t17-,18+
CAS Number1035270-39-3
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Ordering Information

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FormulationSolid powder 
Purity98% 
Storage-20 ºC for 3 years 
SolubilitySoluble in DMSO 
Handling
Shipping ConditionShipped under ambient temperature 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

010820 - AZD4547 | CAS 1035270-39-3

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