Abexinostat is a novel hydroxamate-based HDACi that showed broad spectrum anticancer activities in preclinical studies.
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Name | Abexinostat |
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Iupac Chemical Name | 3-[(Dimethylamino)methyl]-N-[2-[4-[(hydroxyamino)carbonyl]phenoxy]ethyl]-2-benzofurancarboxamide |
Synonyms | PCI 24781;PCI-24781 |
Molecular Formula | C21H23N3O5 |
Molecular Weight | 397.42 |
Smile | O=C(C1=C(CN(C)C)C2=CC=CC=C2O1)NCCOC3=CC=C(C(NO)=O)C=C3 |
InChiKey | MAUCONCHVWBMHK-UHFFFAOYSA-N |
InChi | InChI=1S/C21H23N3O5/c1-24(2)13-17-16-5-3-4-6-18(16)29-19(17)21(26)22-11-12-28-15-9-7-14(8-10-15)20(25)23-27/h3-10,27H,11-13H2,1-2H3,(H,22,26)(H,23,25) |
CAS Number | 783355-60-2 |
Related CAS |
Packaging | Price | Availability | Purity | Shipping Time |
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Bulk | Enquiry | Enquiry | Enquiry |
Formulation | off-white solid |
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Purity | 96% |
Storage | 3 years -20ºCpowder |
Solubility | Soluble in DMSO,DMF |
Handling | |
Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
HS Code |
Targets | |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study |