Acoramidis hydrochloride
Catalog No: 24068
CAS Number: 2242751-53-5
Purity: ≧98.0%
Acoramidis is an oral, potent, and highly selective small molecule transthyretin (TTR) stabilizer designed to mimic the protective function of the T119M mutation in TTR, maintain the normal tetramer conformation of TTR protein, and prevent the production of toxic amyloid protein.
For research use only. We do not sell to patients.
Chemical Information
| Name | Acoramidis hydrochloride |
|---|---|
| Iupac Chemical Name | 3-(3-(3,5-dimethyl-1H-pyrazol-4-yl)propoxy)-4-fluorobenzoic acid hydrochloride |
| Synonyms | Acoramidis hydrochloride ; AG-10 hydrochloride ; AG10 hydrochloride; AG 10 hydrochloride |
| Molecular Formula | C15H18ClFN2O3 |
| Molecular Weight | 328.77 |
| Smile | O=C(O)C1=CC=C(F)C(OCCCC2=C(C)NN=C2C)=C1.[H]Cl |
| InChiKey | MGFZEARHINUOMX-UHFFFAOYSA-N |
| InChi | InChI=1S/C15H17FN2O3.ClH/c1-9-12(10(2)18-17-9)4-3-7-21-14-8-11(15(19)20)5-6-13(14)16;/h5-6,8H,3-4,7H2,1-2H3,(H,17,18)(H,19,20);1H |
| CAS Number | 2242751-53-5 |
| Related CAS | 2242751-53-5 |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Off-white solid |
|---|---|
| Purity | ≧98.0% |
| Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
| Solubility | Soluble in DMSO (DMSO : ≥ 100 mg/mL) |
| Handling | Refer to MSDS |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code | 2934200090 |
Coming soon.
| Targets | transthyretin (TTR) stabilizer |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
