Amuvatinib is a potent and multi-targeted inhibitor of c-Kit, PDGFR and Flt3 with IC50 of 10 nM, 40 nM and 81 nM, respectively.
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Chemical Information
Name | Amuvatinib |
Iupac Chemical Name | N-(1,3-benzodioxol-5-ylmethyl)-4-([1]benzofuro[3,2-d]pyrimidin-4-yl)piperazine-1-carbothioamide |
Synonyms | MP-470; MP 470; MP470; HPK 56 |
Molecular Formula | C23H21N5O3S |
Molecular Weight | 447.510 |
Smile | C1CN(CCN1C2=NC=NC3=C2OC4=CC=CC=C43)C(=S)NCC5=CC6=C(C=C5)OCO6 |
InChiKey | FOFDIMHVKGYHRU-UHFFFAOYSA-N |
InChi | InChI=1S/C23H21N5O3S/c32-23(24-12-15-5-6-18-19(11-15)30-14-29-18)28-9-7-27(8-10-28)22-21-20(25-13-26-22)16-3-1-2-4-17(16)31-21/h1-6,11,13H,7-10,12,14H2,(H,24,32) |
CAS Number | 850879-09-3 |
Related CAS | |
Ordering Information
Packaging | Price | Availability | Purity | Shipping Time |
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Formulation | Solid powder |
Purity | 98% |
Storage | -20 ºC for 3 years |
Solubility | Soluble in DMSO |
Handling | |
Shipping Condition | Shipped under ambient temperature |
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Mechanism | |
Cell study | |
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