Anle138b
Catalog No: 171553
CAS Number: 882697-00-9
Purity: ≧98.0%
Anle138b is an oral, brain-penetrant, general inhibitor of protein aggregation. It was identified in a high-throughput screen for small-molecule inhibitors of α-synuclein and prion protein oligomerization. The compound is being developed for treatment of the rapidly progressing synucleinopathy multiple-system atrophy (MSA) and for Parkinson's disease (PD).
For research use only. We do not sell to patients.
Chemical Information
| Name | Anle138b |
|---|---|
| Iupac Chemical Name | 5-(1,3-benzodioxol-5-yl)-3-(3-bromophenyl)-1H-pyrazole |
| Synonyms | Anle138b ; Anle 138b ; Anle-138b ; Emrusolmin |
| Molecular Formula | C16H11BrN2O2 |
| Molecular Weight | C16H11BrN2O2 |
| Smile | BrC1=CC(C2=NNC(C3=CC=C(OCO4)C4=C3)=C2)=CC=C1 |
| InChiKey | RCQIIBJSUWYYFU-UHFFFAOYSA-N |
| InChi | InChI=1S/C16H11BrN2O2/c17-12-3-1-2-10(6-12)13-8-14(19-18-13)11-4-5-15-16(7-11)21-9-20-15/h1-8H,9H2,(H,18,19) |
| CAS Number | 882697-00-9 |
| Related CAS | 882697-00-9 |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Off-white solid |
|---|---|
| Purity | ≧98.0% |
| Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
| Solubility | Soluble in DMSO |
| Handling | Refer to MSDS |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code | 2934200090 |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
