Anlotinib HCl ( AL-3818 )
Catalog No: 1811211
CAS Number: 1360460-82-7
Purity: ≧98.0%
Anlotinib is a novel oral tyrosine kinase inhibitor (TKI) targeting c-kit, platelet-derived growth factor receptors, fibroblast growth factor receptor, and vascular endothelial growth factor receptor with potential antineoplastic and anti-angiogenic activities.
For research use only. We do not sell to patients.
Chemical Information
| Name | Anlotinib HCl ( AL-3818 ) |
|---|---|
| Iupac Chemical Name | 1-(((4-((4-fluoro-2-methyl-1H-indol-5-yl)oxy)-6-methoxyquinolin-7-yl)oxy)methyl)cyclopropan-1-amine dihydrochloride |
| Synonyms | AL3818 ; AL-3818 ; AL 3818 ; Anlotinib ; Anlotinib HCl ; Anlotinib dihydrochloride ; Catequentinib |
| Molecular Formula | C23H24Cl2FN3O3 |
| Molecular Weight | 480.3614 |
| Smile | NC1(COC2=C(OC)C=C3C(OC4=C(F)C5=C(NC(C)=C5)C=C4)=CC=NC3=C2)CC1.[H]Cl.[H]Cl |
| InChiKey | UUAKQNIPIXQZFN-UHFFFAOYSA-N |
| InChi | InChI=1S/C23H22FN3O3.2ClH/c1-13-9-15-16(27-13)3-4-19(22(15)24)30-18-5-8-26-17-11-21(20(28-2)10-14(17)18)29-12-23(25)6-7-23;;/h3-5,8-11,27H,6-7,12,25H2,1-2H3;2*1H |
| CAS Number | 1360460-82-7 |
| Related CAS | 1058156-90-3 (free base) 1360460-82-7 (HCl) |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Off-white solid to white solid |
|---|---|
| Purity | ≧98.0% |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Wate 96 mg/mL (199.85 mM) ；Ethanol Insoluble ; DMSO 48 mg/mL (99.93 mM). |
| Handling | Refer to MSDS operation |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code | 2934200090 |
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
