Arimoclomol maleate
Catalog No: 188281
CAS Number: 289893-26-1
Purity: 98%
Arimoclomol, also known as BRX-220, is potentially useful for the treatment of Niemann-Pick disease type C (NP-C). Arimoclomol is a small molecule that increases levels of the heat-shock protein 70 (HSP70), a chaperone that helps to fold glucocerebrosidase (GBA), the enzyme that is faulty in people with Gaucher.
Arimoclomol maleate,Bulk in stock, contact us by email for the bulk quotation.
For research use only. We do not sell to patients.
Chemical Information
| Name | Arimoclomol maleate |
|---|---|
| Iupac Chemical Name | (R,Z)-3-(chloro((2-hydroxy-3-(piperidin-1-yl)propoxy)imino)methyl)pyridine 1-oxide maleate |
| Synonyms | Arimoclomol maleate ; BRX-220 ; BRX 220 ; BRX220 ; BRX-345 ; BRX 345 ; BRX345. |
| Molecular Formula | C18H24ClN3O7 |
| Molecular Weight | 429.854 |
| Smile | Cl/C(C1=C[N+]([O-])=CC=C1)=N\OC[C@H](O)CN2CCCCC2.O=C(O)/C=C\C(O)=O |
| InChiKey | OHUSJUJCPWMZKR-GARNONDBSA-N |
| InChi | InChI=1S/C14H20ClN3O3.C4H4O4/c15-14(12-5-4-8-18(20)9-12)16-21-11-13(19)10-17-6-2-1-3-7-17;5-3(6)1-2-4(7)8/h4-5,8-9,13,19H,1-3,6-7,10-11H2;1-2H,(H,5,6)(H,7,8)/b16-14-;2-1-/t13-;/m1./s1 |
| CAS Number | 289893-26-1 |
| Related CAS | 289893-25-0 (free base) 289893-26-1 (maleate) |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Off-white solid to white solid |
|---|---|
| Purity | 98% |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
