Avatrombopag maleate is an orally bioavailable, small molecule thrombopoietin receptor agonist that has been developed by Dova Pharmaceuticals for the treatment of thrombocytopenic disorders.
For research use only. We do not sell to patients.
Name | Avatrombopag maleate |
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Iupac Chemical Name | 4-Piperidinecarboxylic acid, 1-(3-chloro-5-(((4-(4-chloro-2-thienyl)-5-(4-cyclohexyl-1- piperazinyl)-2-thiazolyl)amino)carbonyl)-2-pyridinyl)-, (2Z)-2-butenedioate (1:1) |
Synonyms | AKR501 ; AKR 501 ; AKR-501 ; YM477 ; YM-477 ; YM 477 ; AS 1670542 ; AS1670542 ; AS-1670542 ; E5501 ; E-5501 ; E 5501; |
Molecular Formula | C33H38Cl2N6O7S2 |
Molecular Weight | 765.73 |
Smile | O=C(C1CCN(C2=NC=C(C(NC3=NC(C4=CC(Cl)=CS4)=C(N5CCN(C6CCCCC6)CC5)S3)=O)C=C2Cl)CC1)O.O=C(O)/C=C/C(O)=O |
InChiKey | MISPBGHDNZYFNM-WLHGVMLRSA-N |
InChi | InChI=1S/C29H34Cl2N6O3S2.C4H4O4/c30-20-15-23(41-17-20)24-27(37-12-10-35(11-13-37)21-4-2-1-3-5-21)42-29(33-24)34-26(38)19-14-22(31)25(32-16-19)36-8-6-18(7-9-36)28(39)40;5-3(6)1-2-4(7)8/h14-18,21H,1-13H2,(H,39,40)(H,33,34,38);1-2H,(H,5,6)(H,7,8)/b;2-1+ |
CAS Number | 677007-74-8 |
Related CAS |
Packaging | Price | Availability | Purity | Shipping Time |
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Formulation | Off-white solid to white solid |
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Purity | 96% |
Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
Solubility | Soluble in DMSO |
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HS Code |
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Cell study | |
Animal study | |
Clinical study |