Azeliragon (TTP488) is an orally bioavailable small molecule inhibitor of the receptor of AGE (RAGE).
For research use only. We do not sell to patients.
Name | Azeliragon |
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Iupac Chemical Name | 3-(4-(2-butyl-1-(4-(4-chlorophenoxy)phenyl)-1H-imidazol-4-yl)phenoxy)-N,N-diethylpropan-1-amine |
Synonyms | TTP488 ; TTP-488 ; TTP 488 ; PF-04494700 ; PF 04494700 ; PF04494700 ; Azeliragon |
Molecular Formula | C32H38ClN3O2 |
Molecular Weight | 532.13 |
Smile | CCN(CC)CCCOC1=CC=C(C2=CN(C3=CC=C(OC4=CC=C(Cl)C=C4)C=C3)C(CCCC)=N2)C=C1 |
InChiKey | KJNNWYBAOPXVJY-UHFFFAOYSA-N |
InChi | InChI=1S/C32H38ClN3O2/c1-4-7-9-32-34-31(25-10-16-28(17-11-25)37-23-8-22-35(5-2)6-3)24-36(32)27-14-20-30(21-15-27)38-29-18-12-26(33)13-19-29/h10-21,24H,4-9,22-23H2,1-3H3 |
CAS Number | 603148-36-3 |
Related CAS | 1284150-65-7 (2HCl) 603148-36-3 (free base) |
Packaging | Price | Availability | Purity | Shipping Time |
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Bulk | Enquiry | Enquiry | Enquiry |
Formulation | Off-white solid |
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Purity | ≧98.0% |
Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
Solubility | Soluble in DMSO (DMSO : ≥ 100 mg/mL) |
Handling | Refer to MSDS |
Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
HS Code | 2934200090 |
Targets | |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study |