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B-Raf IN 1

Catalog No: 51918
CAS Number: 950736-05-7
Purity: 98% 

B-Raf IN 1 is a highlt potent and selective B-Raf inhibitor with IC50 of 24 nM; equipotent against c-Raf (IC50= 25 nM) 

For research use only. We do not sell to patients.

Chemical Information

NameB-Raf IN 1
Iupac Chemical NameN-(3-(3-(4-((dimethylamino)methyl)phenyl)pyrazolo[1,5-a]pyrimidin-7-yl)phenyl)-3-(trifluoromethyl)benzamide 
Molecular FormulaC29H24F3N5O 
Molecular Weight515.53 
SmileO=C(NC1=CC=CC(C2=CC=NC3=C(C4=CC=C(CN(C)C)C=C4)C=NN23)=C1)C5=CC=CC(C(F)(F)F)=C5
InChiKeyAIWJVLQNYNCDSL-UHFFFAOYSA-N
InChiInChI=1S/C29H24F3N5O/c1-36(2)18-19-9-11-20(12-10-19)25-17-34-37-26(13-14-33-27(25)37)21-5-4-8-24(16-21)35-28(38)22-6-3-7-23(15-22)29(30,31)32/h3-17H,18H2,1-2H3,(H,35,38)
CAS Number950736-05-7
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Ordering Information

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Formulationyellow solid 
Purity98% 
Storage3 years -20ºCpowder 
SolubilitySoluble in DMSO 
Handling
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

51918 - B-Raf IN 1 | CAS 950736-05-7

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