BAM 7
Catalog No: 16071006
CAS Number: 331244-89-4
Purity: 98% by HPLC
BAM 7 is a Bax activator (EC50 = 3.3 M). BCL-2 family proteins are key regulators of the apoptotic pathway. Antiapoptotic members sequester the BCL-2 homology 3 (BH3) death domains of proapoptotic members such as BAX to maintain cell survival. The antiapoptotic BH3-binding groove has been successfully targeted to reactivate apoptosis in cancer.
For research use only. We do not sell to patients.
Chemical Information
| Name | BAM 7 |
|---|---|
| Iupac Chemical Name | (E)-4-(2-(2-ethoxyphenyl)hydrazono)-5-methyl-2-(4-phenylthiazol-2-yl)-2,4-dihydro-3H-pyrazol-3-one |
| Synonyms | BAM 7; BAM-7 |
| Molecular Formula | C21H19N5O2S |
| Molecular Weight | 405.476 |
| Smile | C(C)OC1=C(C=CC=C1)N\N=C/1\C(N(N=C1C)C=1SC=C(N1)C1=CC=CC=C1)=O |
| InChiKey | KOCVKGYKBLJEPK-LYBHJNIJSA-N |
| InChi | InChI=1S/C21H19N5O2S/c1-3-28-18-12-8-7-11-16(18)23-24-19-14(2)25-26(20(19)27)21-22-17(13-29-21)15-9-5-4-6-10-15/h4-13,23H,3H2,1-2H3/b24-19+ |
| CAS Number | 331244-89-4 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | 98% by HPLC |
| Storage | -20 ºC for 3 years |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
