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BAR-501

Catalog No: 179821
CAS Number: 1632118-69-4
Purity: 98.0%

BAR-501 is a selective GPBAR1 agonist devoid of any FXR agonistic activity. BAR501 effectively reduced hepatic perfusion pressure and counteracted the vasoconstriction activity of norepinephrine.

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Chemical Information

NameBAR-501
Iupac Chemical Name(3R,5S,6S,7S,8S,9S,10S,13R,14S,17R)-6-ethyl-17-((R)-5-hydroxypentan-2-yl)-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol
SynonymsBAR-501; BAR 501; BAR501.
Molecular FormulaC26H46O3
Molecular Weight406.651
SmileC(C)[C@H]1[C@@H]2C[C@@H](CC[C@@]2([C@H]2CC[C@@]3([C@H](CC[C@H]3[C@@H]2[C@H]1O)[C@H](C)CCCO)C)C)O
InChiKeyDQBAHTQWQZRMFH-CRPAWOMZSA-N
InChiInChI=1S/C26H46O3/c1-5-18-22-15-17(28)10-12-26(22,4)21-11-13-25(3)19(16(2)7-6-14-27)8-9-20(25)23(21)24(18)29/h16-24,27-29H,5-15H2,1-4H3/t16-,17-,18+,19-,20+,21+,22+,23+,24+,25-,26-/m1/s1
CAS Number1632118-69-4
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Ordering Information

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Formulationoff-white solid
Purity98.0%
Storage-20 ℃ for 3 years
SolubilitySoluble in DMSO
Handling
Shipping ConditionShipped under ambient temperature
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

179821 - BAR-501 | CAS 1632118-69-4

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