BGB-15025
Catalog No: 171452
CAS Number: 2766481-17-6
Purity: ≧98.0%
BGB-15025 is a potent and selective HPK1 inhibitor that is efficacious as a single agent or in combination with PD-1 antibody in multiple tumor models.
For research use only. We do not sell to patients.
Chemical Information
| Name | BGB-15025 |
|---|---|
| Iupac Chemical Name | (R)-4-(5-amino-6-((1-(1-methylpiperidin-4-yl)-1H-pyrazol-4-yl)oxy)pyrazin-2-yl)-N-(2-(3-fluoropyrrolidin-1-yl)ethyl)-2,6-dimethylbenzamide |
| Synonyms | BGB 15025 ; BGB-15025 ; BGB15025 |
| Molecular Formula | C28H37FN8O2 |
| Molecular Weight | 536.64 |
| Smile | NC1=NC=C(C2=CC(C)=C(C(NCCN3CC[C@@H](F)C3)=O)C(C)=C2)N=C1OC4=CN(C5CCN(C)CC5)N=C4 |
| InChiKey | IGTYEXMPMYGLTR-OAQYLSRUSA-N |
| InChi | InChI=1S/C28H37FN8O2/c1-18-12-20(13-19(2)25(18)27(38)31-7-11-36-10-4-21(29)16-36)24-15-32-26(30)28(34-24)39-23-14-33-37(17-23)22-5-8-35(3)9-6-22/h12-15,17,21-22H,4-11,16H2,1-3H3,(H2,30,32)(H,31,38)/t21-/m1/s1 |
| CAS Number | 2766481-17-6 |
| Related CAS | 2766481-17-6 |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | ≧98.0% |
| Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
| Solubility | Soluble in DMSO |
| Handling | Refer to MSDS |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code | 2934200090 |
Coming soon.
| Targets | HPK1 inhibitor |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study | Phase 1 Clinical Trial |
Not available
Chemical Structure
