BI-847325
Catalog No: 83101
CAS Number: 1207293-36-4
Purity: 95%
BI-847325 is an orally bioavailable, and selective dual MEK/Aurora kinase inhibitor with IC50 of 3 nM, 15 nM, 25 nM, and 4 nM for Xenopus laevis Aurora B, human Aurora A and Aurora C, as well as human MEK1 and MEK2, respectively.
For research use only. We do not sell to patients.
Chemical Information
| Name | BI-847325 |
|---|---|
| Iupac Chemical Name | (Z)-3-(3-((4-((dimethylamino)methyl)phenylamino)(phenyl)methylene)-2-oxoindolin-6-yl)-N-ethylpropiolamide |
| Synonyms | (Z)-3-(3-((4-((dimethylamino)methyl)phenylamino)(phenyl)methylene)-2-oxoindolin-6-yl)-N-ethylpropiolamide |
| Molecular Formula | C29H28N4O2 |
| Molecular Weight | 464.56 |
| Smile | CN(C)CC1=CC=C(C=C1)N\C(=C\1/C(NC2=CC(=CC=C12)C#CC(=O)NCC)=O)\C1=CC=CC=C1 |
| InChiKey | FLBNLJLONKAPLR-DQSJHHFOSA-N |
| InChi | InChI=1S/C29H28N4O2/c1-4-30-26(34)17-13-20-12-16-24-25(18-20)32-29(35)27(24)28(22-8-6-5-7-9-22)31-23-14-10-21(11-15-23)19-33(2)3/h5-12,14-16,18,31H,4,19H2,1-3H3,(H,30,34)(H,32,35)/b28-27- |
| CAS Number | 1207293-36-4 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | 95% |
| Storage | -20 ºC for 3 years |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
