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BIX 02189

Catalog No: 111912
CAS Number: 1265916-41-3
Purity: 98% 

BIX 02189 is a selective MEK5/ERK5 inhibitor with an IC50 of 59 nM, which was reported to inhibit catalytic function of purified, MEK5 enzyme. 

For research use only. We do not sell to patients.

Chemical Information

NameBIX 02189
Iupac Chemical Name(Z)-3-(((3-((dimethylamino)methyl)phenyl)amino)(phenyl)methylene)-N,N-dimethyl-2-oxoindoline-6-carboxamide 
SynonymsBIX02189; BIX-02189 
Molecular FormulaC27H28N4O2 
Molecular Weight440.53682 
SmileO=C(C1=CC(NC/2=O)=C(C=C1)C2=C(NC3=CC=CC(CN(C)C)=C3)/C4=CC=CC=C4)N(C)C
InChiKeyHOMJAAIVTDVQJA-IZHYLOQSSA-N
InChiInChI=1S/C27H28N4O2/c1-30(2)17-18-9-8-12-21(15-18)28-25(19-10-6-5-7-11-19)24-22-14-13-20(27(33)31(3)4)16-23(22)29-26(24)32/h5-16,28H,17H2,1-4H3,(H,29,32)/b25-24-
CAS Number1265916-41-3
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Ordering Information

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FormulationSolid powder 
Purity98% 
Storage-20 ºC for 3 years 
SolubilitySoluble in DMSO 
Handling
Shipping ConditionShipped under ambient temperature 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

111912 - BIX 02189 | CAS 1265916-41-3

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