BI 1015550 ( Nerandomilast ) is an oral, preferential inhibitor of phosphodiesterase 4B (PDE4B) that is being investigated as a potential treatment for idiopathic pulmonary fibrosis (IPF) and progressive pulmonary fibrosis (PPF). BI 1015550 ( Nerandomilast ) represents the first molecule in a new class of PDE4B inhibitors.
For research use only. We do not sell to patients.
Name | BI 1015550 ( Nerandomilast ) |
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Iupac Chemical Name | 1-[[(5R)-2-[4-(5-Chloro-2-pyrimidinyl)-1-piperidinyl]-6,7-dihydro-5-oxidothieno[3,2-d]pyrimidin-4-yl]amino]cyclobutanemethanol |
Synonyms | BI 1015550 ; BI1015550 ; BI-1015550 ;Nerandomilast |
Molecular Formula | C20H25ClN6O2S |
Molecular Weight | 448.97 |
Smile | OCC1(NC2=C3C(CC[S@]3=O)=NC(N4CCC(C5=NC=C(Cl)C=N5)CC4)=N2)CCC1 |
InChiKey | UHYCLWAANUGUMN-SSEXGKCCSA-N |
InChi | InChI=1S/C20H25ClN6O2S/c21-14-10-22-17(23-11-14)13-2-7-27(8-3-13)19-24-15-4-9-30(29)16(15)18(25-19)26-20(12-28)5-1-6-20/h10-11,13,28H,1-9,12H2,(H,24,25,26)/t30-/m1/s1 |
CAS Number | 1423719-30-5 |
Related CAS | 1423719-30-5 |
Packaging | Price | Availability | Purity | Shipping Time |
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Bulk | Enquiry | Enquiry | Enquiry |
Formulation | Off-white solid |
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Purity | ≧98.0% |
Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
Solubility | Soluble in DMSO |
Handling | Refer to MSDS |
Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
HS Code | 2934200090 |
Targets | |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study |