BI 2536
Catalog No: 52616
CAS Number: 755038-02-9
Purity: 98%
BI2536 is a potent Plk1 inhibitor with IC50 of 0.83 nM, BI2536 shows 4- and 11-fold greater selectivity against Plk2 and Plk3; BI2536 also is a BRD4 inhibitor(IC50= 25 nM).
For research use only. We do not sell to patients.
Chemical Information
| Name | BI 2536 |
|---|---|
| Molecular Formula | C28H39N7O3 |
| Molecular Weight | 521.65 |
| Smile | CC[C@H]1C(=O)Nc2cnc(nc2N1C3CCCC3)Nc4ccc(cc4OC)C(=O)NC5CCNCC5 |
| InChiKey | HDNJDRTZRRBORL-NRFANRHFSA-N |
| InChi | InChI=1S/C26H35N7O3/c1-3-21-25(35)30-20-15-28-26(32-23(20)33(21)18-6-4-5-7-18)31-19-9-8-16(14-22(19)36-2)24(34)29-17-10-12-27-13-11-17/h8-9,14-15,17-18,21,27H,3-7,10-13H2,1-2H3,(H,29,34)(H,30,35)(H,28,31,32)/t21-/m0/s1 |
| CAS Number | 755038-02-9 |
| MDL | MFCD18711693 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Purity | 98% |
|---|---|
| Handling | |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
