BLU-285
编号: 1781003
Cas号: 1703793-34-3
纯度: 98.0%
BLU-285 is a potent and selective inhibitor of PDGFR D842V and KIT Exon 17 mutants and is being developed as a highly targeted therapy for SM, a disorder of the mast cells in which a KIT Exon 17 mutation is the primary driver of disease.
For research use only. We do not sell to patients.
化学信息
| 名称 | BLU-285 |
|---|---|
| Iupac 化学名称 | (S)-1-(4-fluorophenyl)-1-(2-(4-(6-(1-methyl-1H-pyrazol-4-yl)pyrrolo[2,1-f][1,2,4]triazin-4-yl)piperazin-1-yl)pyrimidin-5-yl)ethan-1-amine |
| 同义词 | BLU-285|BLU 285|BLU285|Avapritinib |
| 分子式 | C26H27FN10 |
| 分子量 | 498.5704 |
| Smile | FC1=CC=C(C=C1)[C@](C)(N)C=1C=NC(=NC1)N1CCN(CC1)C1=NC=NN2C1=CC(=C2)C=2C=NN(C2)C |
| InChiKey | DWYRIWUZIJHQKQ-SANMLTNESA-N |
| InChi | InChI=1S/C26H27FN10/c1-26(28,20-3-5-22(27)6-4-20)21-13-29-25(30-14-21)36-9-7-35(8-10-36)24-23-11-18(16-37(23)33-17-31-24)19-12-32-34(2)15-19/h3-6,11-17H,7-10,28H2,1-2H3/t26-/m0/s1 |
| Cas号 | 1703793-34-3 |
| Related CAS |
订购信息
| Packaging | 价格 | Availability | 纯度 | Shipping Time |
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| Bulk | 询价 | 询价 | 询价 |
