BMS-794833 is a potent ATP competitive inhibitor of Met/VEGFR2 with IC50 of 1.7/15 nM; also inhibits Ron, Axl and Flt3 with IC50 of<3 nM; a prodrug of BMS-817378.
For research use only. We do not sell to patients.
Name | BMS-794833 |
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Iupac Chemical Name | N-(4-((2-amino-3-chloropyridin-4-yl)oxy)-3-fluorophenyl)-5-(4-fluorophenyl)-4-oxo-1,4-dihydropyridine-3-carboxamide |
Synonyms | N/A |
Molecular Formula | C23H15ClF2N4O3 |
Molecular Weight | 468.84 |
Smile | NC1=NC=CC(=C1Cl)OC1=C(C=C(C=C1)NC(=O)C1=CNC=C(C1=O)C1=CC=C(C=C1)F)F |
InChiKey | PDYXPCKITKHFOZ-UHFFFAOYSA-N |
InChi | InChI=1S/C23H15ClF2N4O3/c24-20-19(7-8-29-22(20)27)33-18-6-5-14(9-17(18)26)30-23(32)16-11-28-10-15(21(16)31)12-1-3-13(25)4-2-12/h1-11H,(H2,27,29)(H,28,31)(H,30,32) |
CAS Number | 1174046-72-0 |
Related CAS |
Packaging | Price | Availability | Purity | Shipping Time |
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Bulk | Enquiry | Enquiry | Enquiry |
Formulation | solid |
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Purity | 98% |
Storage | 3 years -20ºCpowder |
Solubility | 5mg/ml in DMSO |
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HS Code |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study |