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BMS-816336

Catalog No: 19351
CAS Number: 1009583-20-3
Purity: >98%

BMS-816336是一种口服活性、有效和选择性的11β-HSD1抑制剂。BMS- 816336显示人类活动对11β-羟甾类脱氢酶1型(11β-HSD1)酶(IC50 3.0 nM)> 10000倍选择性比人类11β-羟甾类脱氢酶2型(11β-HSD2)。

For research use only. We do not sell to patients.

Chemical Information

NameBMS-816336
Iupac Chemical Name2-((1R,2R,3S,5R,6R)-6-hydroxy-2-phenyladamantan-2-yl)-1-(3-hydroxyazetidin-1-yl)ethan-1-one
SynonymsBMS-816336; BMS 816336; BMS816336.
Molecular FormulaC21H27NO3
Molecular Weight341.451
SmileOC1CN(C(C[C@]2(C3=CC=CC=C3)[C@H]4C[C@@H]5[C@@H](O)C(C4)C[C@H]2C5)=O)C1
InChiKeyOAAZMUGLOXGVNH-MEMOLBONSA-N, OAAZMUGLOXGVNH-CCVYDFRESA-N
InChiInChI=1S/C21H27NO3/c23-18-11-22(12-18)19(24)10-21(15-4-2-1-3-5-15)16-6-13-7-17(21)9-14(8-16)20(13)25/h1-5,13-14,16-18,20,23,25H,6-12H2/t13-,14?,16-,17+,20-,21-/m1/s1
CAS Number1009583-20-3
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Ordering Information

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Formulation类白色至白色固体
Purity>98%
Storage短期可在0-4度保存,数天至数月;长期可在-20度保存三年。
Solubility可溶于DMSO
Handling
Shipping Condition可在常温下运输
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

19351 - BMS-816336  | CAS 1009583-20-3

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