BMVC-8C3O
Catalog No: 2071550
CAS Number: 1301708-12-2
Purity: 98% Min.
BMVC-8C3O is a DNA G-quadruplexe (G4) ligand which can induce topological conversion of non-parallel to parallel forms in human telomeric DNA G4s.
For research use only. We do not sell to patients.
Chemical Information
| Name | BMVC-8C3O |
|---|---|
| Iupac Chemical Name | 4,4'-((1E,1'E)-(9-(2-(2-(2-(2-(1-methylpiperidin-1-ium-1-yl)ethoxy)ethoxy)ethoxy)ethyl)-9H-carbazole-3,6-diyl)bis(ethene-2,1-diyl))bis(1-methylpyridin-1-ium) iodide |
| Synonyms | BMVC-8C3O; BMVC 8C3O; BMVC8C3O; |
| Molecular Formula | C42H53I3N4O3 |
| Molecular Weight | 1042.6244 |
| Smile | C[N+]1(CCOCCOCCOCCN2C3=C(C4=C2C=CC(/C=C/C5=CC=[N+](C)C=C5)=C4)C=C(/C=C/C6=CC=[N+](C)C=C6)C=C3)CCCCC1.[I-].[I-].[I-] |
| InChiKey | DKMJOQQQBQBOMV-UHFFFAOYSA-K |
| InChi | InChI=1S/C42H53N4O3.3HI/c1-43-19-15-35(16-20-43)7-9-37-11-13-41-39(33-37)40-34-38(10-8-36-17-21-44(2)22-18-36)12-14-42(40)45(41)23-27-47-29-31-49-32-30-48-28-26-46(3)24-5-4-6-25-46;;;/h7-22,33-34H,4-6,23-32H2,1-3H3;3*1H/q+3;;;/p-3 |
| CAS Number | 1301708-12-2 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | 98% Min. |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
1: Wang ZF, Li MH, Chen WW, Hsu ST, Chang TC. A novel transition pathway of ligand-induced topological conversion from hybrid forms to parallel forms of human telomeric G-quadruplexes. Nucleic Acids Res. 2016 May 5;44(8):3958-68. doi: 10.1093/nar/gkw145. Epub 2016 Mar 14. PMID: 26975658; PMCID: PMC4856992.
2: Wang ZF, Chang TC. Molecular engineering of G-quadruplex ligands based on solvent effect of polyethylene glycol. Nucleic Acids Res. 2012 Sep 1;40(17):8711-20. doi: 10.1093/nar/gks578. Epub 2012 Jun 26. PMID: 22735707; PMCID: PMC3458535.
Chemical Structure
