Bimiralisib,也被称为PQR309,是一种口服生物可用的磷脂- 3 -激酶抑制剂(PI3K)和哺乳动物雷帕霉素靶(mTOR)的抑制剂,具有潜在的抗肿瘤活性。
For research use only. We do not sell to patients.
Name | Bimiralisib |
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Iupac Chemical Name | 5-(4,6-dimorpholino-1,3,5-triazin-2-yl)-4-(trifluoromethyl)pyridin-2-amine |
Synonyms | PQR309; PQR-309; PQR309; Bimiralisib free base |
Molecular Formula | C17H20F3N7O2 |
Molecular Weight | 411.3892 |
Smile | O1CCN(CC1)C1=NC(=NC(=N1)N1CCOCC1)C=1C(=CC(=NC1)N)C(F)(F)F |
InChiKey | ADGGYDAFIHSYFI-UHFFFAOYSA-N |
InChi | InChI=1S/C17H20F3N7O2/c18-17(19,20)12-9-13(21)22-10-11(12)14-23-15(26-1-5-28-6-2-26)25-16(24-14)27-3-7-29-8-4-27/h9-10H,1-8H2,(H2,21,22) |
CAS Number | 1225037-39-7 |
Related CAS |
Packaging | Price | Availability | Purity | Shipping Time |
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Bulk | Enquiry | Enquiry | Enquiry |
Formulation | 类白色至白色固体 |
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Purity | 98% |
Storage | 短期可在0-4度保存,数天至数月;长期可在-20度保存三年。 |
Solubility | 可溶于DMSO |
Handling | |
Shipping Condition | 可在常温下运输 |
HS Code |
Targets | |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study |