Brepocitinib ( PF-06700841 )

Catalog No: 232251

CAS Number: 1883299-62-4

Purity: ≧98.0%

Brepocitinib is a potential first-in-class dual, selective inhibitor of TYK2 and JAK1 with IC50s of 17 nM and 23 nM, respectively.

For research use only. We do not sell to patients.

Name	Brepocitinib ( PF-06700841 )
Iupac Chemical Name	((S)-2,2-difluorocyclopropyl)((1R,5S)-3-(2-((1-methyl-1H-pyrazol-4-yl)amino)pyrimidin-4-yl)-3,8-diazabicyclo[3.2.1]octan-8-yl)methanone
Synonyms	PF-06700841 ; PF 06700841 ; PF06700841 ; Brepocitinib
Molecular Formula	C18H21F2N7O
Molecular Weight	389.40
Smile	O=C([C@H]1C(F)(F)C1)N2[C@@]3([H])CN(C4=NC(NC5=CN(C)N=C5)=NC=C4)C[C@]2([H])CC3
InChiKey	BUWBRTXGQRBBHG-MJBXVCDLSA-N
InChi	InChI=1S/C18H21F2N7O/c1-25-8-11(7-22-25)23-17-21-5-4-15(24-17)26-9-12-2-3-13(10-26)27(12)16(28)14-6-18(14,19)20/h4-5,7-8,12-14H,2-3,6,9-10H2,1H3,(H,21,23,24)/t12-,13+,14-/m0/s1
CAS Number	1883299-62-4
Related CAS	2140301-96-6 (tosylate) 1883299-62-4 (free base)

Packaging	Price	Availability	Purity	Shipping Time
Bulk		Enquiry	Enquiry	Enquiry

Formulation	Solid powder
Purity	≧98.0%
Storage	Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years).
Solubility	Soluble in DMSO
Handling	Refer to MSDS
Shipping Condition	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
HS Code	2934200090

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