Bunamidine hydrochloride
Bunamidine is a anti-parasitic drug, which was approved by FDA for the treatment of tapeworms in cats and dogs (Scolaban 400 tablets).
For research use only. We do not sell to patients.
Chemical Information
| Name | Bunamidine hydrochloride |
|---|---|
| Iupac Chemical Name | 1-Naphthalenecarboximidamide, N,N-dibutyl-4-(hexyloxy)-, monohydrochloride |
| Synonyms | Bunamidine hydrochloride; Bunamidine HCl; BW62415; BW-62415; BW 62415; Scolaban |
| Molecular Formula | C25H39ClN2O |
| Molecular Weight | 419.04 |
| Smile | N=C(C1=C2C=CC=CC2=C(OCCCCCC)C=C1)N(CCCC)CCCC.[H]Cl |
| InChiKey | PBYJDHRFPFHVKZ-UHFFFAOYSA-N |
| InChi | InChI=1S/C25H38N2O.ClH/c1-4-7-10-13-20-28-24-17-16-23(21-14-11-12-15-22(21)24)25(26)27(18-8-5-2)19-9-6-3;/h11-12,14-17,26H,4-10,13,18-20H2,1-3H3;1H |
| CAS Number | 1055-55-6 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | 98% Min. |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code |
| Targets | |
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| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
1: Larionova TK, Kudasheva FKh, Bogoliuk GB, Afanaséva LI. Opredelenie promezhutochnykh produktov sinteza bunamidina gidrokhlorida v vozdukhe rabocheĭ rabocheĭ zony metodom vysokoéffectivnoĭ zhidkostnoĭ khromatografii [Evaluation of intermediate products of bunamidine hydrochloride synthesis in the workplace air by high performance liquid chromatography method]. Gig Sanit. 1993 Oct;(10):70-1. Russian. PMID: 8163245.
2: Cruthers LR, Linkenheimer WH, Maplesden DC. Taeniacidal efficacy of SQ 21,704 in dogs by various types of oral administration and in comparison with niclosamide and bunamidine hydrochloride. Am J Vet Res. 1979 May;40(5):676-8. PMID: 573081.
3: Thakur AS, Prezioso U, Marchevsky N. Echinococcus granulosus: ovicidal activity of praziquantel and bunamidine hydrochloride. Exp Parasitol. 1979 Apr;47(2):131-3. doi: 10.1016/0014-4894(79)90066-3. PMID: 571349.
4: Todd KS Jr, Howland TP, Woerpel RW. Activity of uredofos, niclosamide, bunamidine hydrochloride, and arecoline hydrobromide against Mesocestoides corti in experimentally infected dogs. Am J Vet Res. 1978 Feb;39(2):315-6. PMID: 564650.
5: Gemmell MA. The Styx Field Trial: effect of treatment of the definitive host for tapeworms on larval forms in the intermediate host. Bull World Health Organ. 1978;56(3):433-43. PMID: 308408; PMCID: PMC2395586.
6: Roberson EL. Comparative effects of uredofos, niclosamide, and bunamidine hydrochloride against tapeworm infections in dogs. Am J Vet Res. 1976 Dec;37(12):1483-4. PMID: 1033722.
7: King AB. Bunamidine hydrochloride in dogs. J Am Vet Med Assoc. 1976 Nov 1;169(9):854, 856, 858. PMID: 988006.
8: Williams JF, Keahey KK. Sudden death associated with treatment of three dogs with bunamidine hydrochloride. J Am Vet Med Assoc. 1976 Apr 15;168(8):689-91. PMID: 944173.
9: Trejos A, Szyfres B, Marchevsky N. Comparative value of arecoline hydrobromide and bunamidine hydrochloride for the treatment of Echinococcus granulosus in dogs. Res Vet Sci. 1975 Sep;19(2):212-3. PMID: 1172623.
10: Andersen FL, Loveless RM, Jensen LA. Efficacy of bunamidine hydrochloride against immature and mature stages of Echinococcus granulosus. Am J Vet Res. 1975 May;36(5):673-5. PMID: 1169897.
11: Williams GF, Colli CW, Leid RW, MacArthur R. The effects of bunamidine hydrochloride on the infectivity of taeniid ova. J Parasitol. 1973 Dec;59(6):1141-4. PMID: 4796811.
12: Cook BR. A field trial with bunamidine hydrochloride as an anthelmintic in the eradication of Echinococcus granulosus, Taenia hydatigena and Taenia ovis in New Zealand. N Z Vet J. 1970 Aug;18(8):152-5. doi: 10.1080/00480169.1970.33886. PMID: 5273618.
13: Williams JF, Trejos A. The influence of gelatin capsules upon the activity of bunamidine hydrochloride against Echinococcus granulosus in dogs. Res Vet Sci. 1970 Jul;11(4):392-4. PMID: 5499329.
14: Blood BD, Moya V, Lelijveld JL. Evaluation of selected drugs for the treatment of canine echinococcosis. Bull World Health Organ. 1968;39(1):67-72. PMID: 5303842; PMCID: PMC2554388.
15: Forbes LS. The efficiency of bunamidine hydrochloride against young Echinococcus granulosus infection in dogs. Vet Rec. 1966 Sep 10;79(11):306-7. doi: 10.1136/vr.79.11.306. PMID: 5970728.
16: HATTON CJ. A NEW TAENIACIDE, BUNAMIDINE HYDROCHLORIDE: ITS EFFICIENCY AGAINST TAENIA PISIFORMIS AND DIPYLIDIUM CANINUM IN THE DOG AND HYDATIGERA TAENIAEFORMIS IN THE CAT. Vet Rec. 1965 Apr 10;77:408-11. PMID: 14330224.
Chemical Structure
