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CFI-400945

Catalog No: 123012
CAS Number: 1338806-73-7
Purity: 98% 

CFI-400945 is an orally available fumarate salt form of CFI-400945, a polo-like kinase 4 (PLK4) inhibitor with potential antineoplastic activity. 

For research use only. We do not sell to patients.

Chemical Information

NameCFI-400945
Iupac Chemical Name(1R,2S)-2-(3-((E)-4-(((2S,6R)-2,6-dimethylmorpholino)methyl)styryl)-1H-indazol-6-yl)-5'-methoxyspiro[cyclopropane-1,3'-indolin]-2'-one 
SynonymsCFI400945; CFI 400945 
Molecular FormulaC37H38N4O7 
Molecular Weight650.72 
SmileC[C@@H]1O[C@@H](CN(C1)CC1=CC=C(/C=C/C2=NNC3=CC(=CC=C23)[C@@H]2C[C@@]23C(NC2=CC=C(C=C32)OC)=O)C=C1)C
InChiKeyDADASRPKWOGKCU-FVTQAUBDSA-N
InChiInChI=1S/C33H34N4O3/c1-20-17-37(18-21(2)40-20)19-23-6-4-22(5-7-23)8-12-29-26-11-9-24(14-31(26)36-35-29)28-16-33(28)27-15-25(39-3)10-13-30(27)34-32(33)38/h4-15,20-21,28H,16-19H2,1-3H3,(H,34,38)(H,35,36)/b12-8+/t20-,21+,28-,33-/m0/s1
CAS Number1338806-73-7
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Ordering Information

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FormulationSolid powder 
Purity98% 
Storage-20 ºC for 3 years 
SolubilitySoluble in DMSO 
Handling
Shipping ConditionShipped under ambient temperature 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

123012 - CFI-400945 | CAS 1338806-73-7

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