CH5424802 Hcl (AF 802 Hcl; Alectinib Hcl) is a potent ALK inhibitor with IC50 of 1.9 nM, sensitive to L1196M mutation.
For research use only. We do not sell to patients.
Name | CH5424802 Hydrochloride |
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Iupac Chemical Name | 9-Ethyl-6,11-dihydro-6,6-dimethyl-8-[4-(4-morpholinyl)-1-piperidinyl]-11-oxo-5H-benzo[b]carbazole-3-carbonitrile hydrochloride |
Molecular Formula | C30H35ClN4O2 |
Molecular Weight | 519.08 |
Smile | Cl.C(C)C1=CC2=C(C(C=3NC4=CC(=CC=C4C3C2=O)C#N)(C)C)C=C1N1CCC(CC1)N1CCOCC1 |
InChiKey | GYABBVHSRIHYJR-UHFFFAOYSA-N |
InChi | InChI=1S/C30H34N4O2.ClH/c1-4-20-16-23-24(17-26(20)34-9-7-21(8-10-34)33-11-13-36-14-12-33)30(2,3)29-27(28(23)35)22-6-5-19(18-31)15-25(22)32-29;/h5-6,15-17,21,32H,4,7-14H2,1-3H3;1H |
CAS Number | 1256589-74-8 |
Related CAS |
Packaging | Price | Availability | Purity | Shipping Time |
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Formulation | off-white solid |
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Purity | 98% |
Storage | 3 years -20ºCpowder |
Solubility | 5mg/ml in DMSO |
Handling | |
Shipping Condition | Shipped under ambient temperature |
HS Code |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study |