CHS-828
Catalog No: 100904
CAS Number: 200484-11-3
Purity: 98%
CHS-828, also known as GMX-1778, is a potent and selective NAMPT inhibitor. CHS-828 inhibits cellular synthesis of NAD. CHS 828 kill tumour cells by inhibiting the nuclear factor-kappaB translocation but unlikely through down-regulation of proteasome. CHS 828 has shown promising anticancer activity in experimental tumor models and primary cultures of cancer cells from patients.
For research use only. We do not sell to patients.
Chemical Information
| Name | CHS-828 |
|---|---|
| Iupac Chemical Name | (E)-1-(6-(4-chlorophenoxy)hexyl)-2-cyano-3-(pyridin-4-yl)guanidine |
| Synonyms | CHS 828; CHS828; GMX-1778; GMX1778; GMX 1778 |
| Molecular Formula | C19H22ClN5O |
| Molecular Weight | 371.86 |
| Smile | ClC1=CC=C(OCCCCCCN/C(=N\C#N)/NC2=CC=NC=C2)C=C1 |
| InChiKey | BOIPLTNGIAPDBY-UHFFFAOYSA-N |
| InChi | InChI=1S/C19H22ClN5O/c20-16-5-7-18(8-6-16)26-14-4-2-1-3-11-23-19(24-15-21)25-17-9-12-22-13-10-17/h5-10,12-13H,1-4,11,14H2,(H2,22,23,24,25) |
| CAS Number | 200484-11-3 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | 98% |
| Storage | -20 ºC for 3 years |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
