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CL-387785

Catalog No: 022202
CAS Number: 194423-06-8
Purity: 98% 

CL-387785 is an irreversible inhibitor of EGFR with IC50 of 370+/-120 pM; is able to overcome resistance caused by the T790M mutation on a functional level.
 

For research use only. We do not sell to patients.

Chemical Information

NameCL-387785
Iupac Chemical NameN-[4-[(3-Bromophenyl)amino]-6-quinazolinyl]-2-butynamide 
SynonymsEKI-785; WAY-EKI 785; CL387785; CL 387785; EKI785; WAY-EKI785; EKI 785 
Molecular FormulaC18H13BrN4O 
Molecular Weight381.23 
SmileCC#CC(NC1=CC2=C(NC3=CC=CC(Br)=C3)N=CN=C2C=C1)=O
InChiKeyBTYYWOYVBXILOJ-UHFFFAOYSA-N
InChiInChI=1S/C18H13BrN4O/c1-2-4-17(24)22-14-7-8-16-15(10-14)18(21-11-20-16)23-13-6-3-5-12(19)9-13/h3,5-11H,1H3,(H,22,24)(H,20,21,23)
CAS Number194423-06-8
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Ordering Information

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FormulationSolid powder 
Purity98% 
Storage-20 ºC for 3 years 
SolubilitySoluble in DMSO 
Handling
Shipping ConditionShipped under ambient temperature 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

022202 - CL-387785 | CAS 194423-06-8

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